Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome

<p>We describe a case of left hand extensor tenosynovitis due to histoplasmosis in a patient with dermatomyositis on chronic immunosuppression. Treatment involved surgical debridement and antifungal therapy. The patient experienced paradoxical worsening of tenosynovial inflammation during de-a...

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Main Authors: T. Riaz, M. Collins, M. Enzler, M. Rizzo, A. N. Schuetz, J. S. Lehman, D. Osmon, I. G. Sia
Format: Article
Language:English
Published: Copernicus Publications 2021-09-01
Series:Journal of Bone and Joint Infection
Online Access:https://jbji.copernicus.org/articles/6/355/2021/jbji-6-355-2021.pdf
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spelling doaj-403c98341f7942d89e27766219b180442021-09-23T09:56:17ZengCopernicus PublicationsJournal of Bone and Joint Infection2206-35522021-09-01635536110.5194/jbji-6-355-2021Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndromeT. Riaz0T. Riaz1M. Collins2M. Enzler3M. Rizzo4A. N. Schuetz5J. S. Lehman6J. S. Lehman7D. Osmon8I. G. Sia9Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USADivisin of Infectious Diseases, University of Arizona Medical Center, Tucson, AZ, USADepartment of Radiology, Mayo Clinic, Rochester, Minnesota, USADivision of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USADivision of Hand Surgery, Mayo Clinic, Rochester, Minnesota, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USADepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, USADepartment of Dermatology, Mayo Clinic, Rochester, Minnesota, USA Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USADivision of Infectious Diseases, Mayo Clinic, Rochester, Minnesota, USA<p>We describe a case of left hand extensor tenosynovitis due to histoplasmosis in a patient with dermatomyositis on chronic immunosuppression. Treatment involved surgical debridement and antifungal therapy. The patient experienced paradoxical worsening of tenosynovial inflammation during de-augmentation of immunosuppression felt to be immune reconstitution inflammatory syndrome.</p>https://jbji.copernicus.org/articles/6/355/2021/jbji-6-355-2021.pdf
collection DOAJ
language English
format Article
sources DOAJ
author T. Riaz
T. Riaz
M. Collins
M. Enzler
M. Rizzo
A. N. Schuetz
J. S. Lehman
J. S. Lehman
D. Osmon
I. G. Sia
spellingShingle T. Riaz
T. Riaz
M. Collins
M. Enzler
M. Rizzo
A. N. Schuetz
J. S. Lehman
J. S. Lehman
D. Osmon
I. G. Sia
Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome
Journal of Bone and Joint Infection
author_facet T. Riaz
T. Riaz
M. Collins
M. Enzler
M. Rizzo
A. N. Schuetz
J. S. Lehman
J. S. Lehman
D. Osmon
I. G. Sia
author_sort T. Riaz
title Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome
title_short Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome
title_full Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome
title_fullStr Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome
title_full_unstemmed Left hand extensor tenosynovitis due to <i>Histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome
title_sort left hand extensor tenosynovitis due to <i>histoplasma capsulatum</i> complicated by immune reconstitution inflammatory syndrome
publisher Copernicus Publications
series Journal of Bone and Joint Infection
issn 2206-3552
publishDate 2021-09-01
description <p>We describe a case of left hand extensor tenosynovitis due to histoplasmosis in a patient with dermatomyositis on chronic immunosuppression. Treatment involved surgical debridement and antifungal therapy. The patient experienced paradoxical worsening of tenosynovial inflammation during de-augmentation of immunosuppression felt to be immune reconstitution inflammatory syndrome.</p>
url https://jbji.copernicus.org/articles/6/355/2021/jbji-6-355-2021.pdf
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