Progressive multifocal leukoence-phalopathy presenting as homonymous hemianopia in a patient with acquired immunodeficiency syndrome

• Main Authors: Amit Pandey, Karishma Bandivdekar, Suresh Ramchandani, Sushama Ramchandani
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2012-01-01
• Series: Indian Journal of Ophthalmology
• Subjects: Accommodation; disaccommodation; mydriasis; phenylephrine hydrochloride; pupil; velocity; Growth; human adult; lens diameter; lens dry weight; lens thickness; lens wet weight; Silicone oil removal; encirclage; 360 retinopexy; oil emulsification; silicone oil tamponade; Age-related macular degeneration; chorodial neovascularization; ocular trauma; polypoidal choroidal vasculopathy; retinal macroaneurysm; submacular hemorrhage; subretinal hemorrhage; tissue plasminogen activator; vitrectomy; Insulin-like growth factor-1; insulin-like growth factor binding protein-3; retinopathy of prematurity; Brilliant Blue G; dextrose normal saline 10%; internal limiting membrane; macular hole; Angle closure; anterior chamber angle; blotchy pigments; glaucomatous optic neuropathy; peripheral anterior synechiae; Cardiff acuity cards; lea grating; visual acuity in pre-verbal children; Contrast sensitivity; contrast visual acuity; retinitis pigmentosa; Bevacizumab; choroidal neovacular membrane; panuveitis; triamcinolone acetonide; Vogt-Koyanagi-Harada syndrome; Spectacles; spectacle dispensing; spectacle dispensing errors; Indian eyes; normative database; retinal nerve fiber layer thickness; spectral domain optical coherence tomography; Bilateral medial rectus palsy; facial diplegia; Moebius sequence; Eclipse retinopathy; epimacular membrane; fundus autofluorescence; optical coherence tomography; Amniotic membrane transplantation; ligneous conjunctivitis; pseudomembrane; topical cyclosporine; Planned posterior assisted levitation; posterior assisted levitation; subluxated cataract; zonular dialysis; Endothelial cell count; phacoemulsification; Werner′s syndrome; Yettrium-Aluminum-Garnet capsulotomy; Cataract surgery; endothelial keratoplasty; Acquired Immunodeficiency Syndrome; demy-elination; homonymous hemianopia; perimetry; progressive multifocal leukoencephalopathy
• Online Access: http://www.ijo.in/article.asp?issn=0301-4738;year=2012;volume=60;issue=6;spage=574;epage=576;aulast=Pandey
• ISSN: 0301-4738; 1998-3689

We present a case of a Human Immunodeficiency Virus (HIV) positive patient who was referred for retinal evaluation to rule out ophthalmic manifestations of Acquired Immunodeficiency Syndrome (AIDS). She complained of some disturbance in vision in both eyes. Fundus examination showed no abnormality. Perimetry, done to rule out optic nerve pathology, showed a left homonymous hemianopia. Magnetic Resonance Imaging (MRI) scan showed features of Progressive Multifocal Leukoencephalopathy (PML). She had no other neurological symptoms or signs.