Effect of L-NAME on the Synthesis of Plasma Fibrinogen in Mice

The effect of nitric oxide (NO) on plasma fibrinogen was investigated by treating mice with oral NG-nitro-L-arginine-methyl ester (L-NAME), a non-selective NO synthase (NOS) inhibitor. Treatment with L-NAME significantly increased the concentration of plasma fibrinogen and hepatic expression of the...

Full description

Bibliographic Details
Main Authors: Yasutaka Takinishi, Masako Okazaki, Katsuji Oguchi
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Journal of Pharmacological Sciences
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861319322200