Genomic African and Native American Ancestry and Chagas Disease: The Bambui (Brazil) Epigen Cohort Study of Aging.

The influence of genetic ancestry on Trypanosoma cruzi infection and Chagas disease outcomes is unknown.We used 370,539 Single Nucleotide Polymorphisms (SNPs) to examine the association between individual proportions of African, European and Native American genomic ancestry with T. cruzi infection a...

Full description

Bibliographic Details
Main Authors: M Fernanda Lima-Costa, James Macinko, Juliana Vaz de Mello Mambrini, Sérgio Viana Peixoto, Alexandre Costa Pereira, Eduardo Tarazona-Santos, Antonio Luiz Pinho Ribeiro
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-05-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4868305?pdf=render