Targeting TF-AKT/ERK-EGFR Pathway Suppresses the Growth of Hepatocellular Carcinoma

Targeting TF-AKT/ERK-EGFR Pathway Suppresses the Growth of Hepatocellular Carcinoma

Tissue factor (TF) is a transmembrane glycoprotein to initiate blood coagulation and frequently overexpressed in a variety of tumors. Our previous study has showed that the expression of TF is upregulated and correlated with prognosis in hepatocellular carcinoma (HCC). However, the role and molecula...

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Main Authors:	Shan-Zhou Huang, Meng-Ning Wei, Jia-Rong Huang, Zi-Jian Zhang, Wen-Ji Zhang, Qi-Wei Jiang, Yang Yang, Huan-Yu Wang, Hui-Lin Jin, Kun Wang, Zi-Hao Xing, Meng-Ling Yuan, Yao Li, Xiao-Shun He, Zhi Shi, Qi Zhou
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2019-03-01
Series:	Frontiers in Oncology
Subjects:	hepatocellular carcinoma tissue factor epidermal growth factor receptor AKT/ERK tumor growth
Online Access:	https://www.frontiersin.org/article/10.3389/fonc.2019.00150/full

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