Expression profile of CYP1A1 and CYP1B1 enzymes in colon and bladder tumors.

BACKGROUND: The cytochrome P450 CYP1A1 and CYP1B1 enzymes are involved in carcinogenesis via activation of pro-carcinogenic compounds to carcinogenic metabolites. CYP1A1 and CYP1B1 have shown elevated levels in human tumors as determined by qRT-PCR and immunohistochemical studies. However studies th...

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Main Authors: Vasilis P Androutsopoulos, Ioannis Spyrou, Achilles Ploumidis, Alexandros Eystathios Papalampros, Michalis Kyriakakis, Demetrios Delakas, Demetrios A Spandidos, Aristidis M Tsatsakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3864999?pdf=render