Alloreactive regulatory T cells allow the generation of mixed chimerism and transplant tolerance

The induction of donor-specific transplant tolerance is one of the main goals of modern immunology. Establishment of a mixed chimerism state in the transplant recipient has proven to be a suitable strategy for the induction of long-term allograft tolerance; however, current experimental recipient pr...

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Bibliographic Details
Main Authors: Paulina eRuiz, Paula eMaldonado, Yessia eHidalgo, Daniela eSauma, Mario eRosemblatt, Maria Rosa eBono
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2015.00596/full