Calcium-sensing receptors regulate cardiomyocyte Ca<sup>2+ </sup>signaling via the sarcoplasmic reticulum-mitochondrion interface during hypoxia/reoxygenation

<p>Abstract</p> <p>Communication between the SR (sarcoplasmic reticulum, SR) and mitochondria is important for cell survival and apoptosis. The SR supplies Ca<sup>2+ </sup>directly to mitochondria via inositol 1,4,5-trisphosphate receptors (IP<sub>3</sub>Rs)...

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Main Authors: Lu Fang-hao, Tian Zhiliang, Zhang Wei-hua, Zhao Ya-jun, Li Hu-lun, Ren Huan, Zheng Hui-shuang, Liu Chong, Hu Guang-xia, Tian Ye, Yang Bao-feng, Wang Rui, Xu Chang-qing
Format: Article
Language:English
Published: BMC 2010-06-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/17/1/50