Plasticity of Naturally Occurring Regulatory T Cells in Allergic Airway Disease Is Modulated by the Transcriptional Activity of <i>Il-6</i>

Plasticity of Naturally Occurring Regulatory T Cells in Allergic Airway Disease Is Modulated by the Transcriptional Activity of <i>Il-6</i>

The impact of naturally occurring regulatory T cells (nTregs) on the suppression or induction of lung allergic responses in mice depends on the nuclear environment and the production of the pro-inflammatory cytokine interleukin 6 (IL-6). These activities were shown to be different in nTregs derived...

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Bibliographic Details
Main Authors: Morgan MacBeth, Anthony Joetham, Erwin W. Gelfand, Michaela Schedel
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
IL-6
naturally occurring T regulatory cells (nTregs)
plasticity
transcriptional regulation
transcription factor binding
Online Access:https://www.mdpi.com/1422-0067/22/9/4582

Internet

https://www.mdpi.com/1422-0067/22/9/4582

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