Transgenic mice exhibiting inducible and spontaneous Cre activities driven by a bovine keratin 5 promoter that can be used for the conditional analysis of basal epithelial cells in multiple organs

Transgenic mice exhibiting inducible and spontaneous Cre activities driven by a bovine keratin 5 promoter that can be used for the conditional analysis of basal epithelial cells in multiple organs

<p>Abstract</p> <p>Background</p> <p>Cre/<it>lox</it>P-mediated genetic modification is the most widely used conditional genetic approach used in the mouse. Engineered Cre and the mutated ligand-binding domain of estrogen receptor fusion recombinase (CreER&l...

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Bibliographic Details
Main Authors: Liang Chih-Chia, You Li-Ru, Chang Junn-Liang, Tsai Ting-Fen, Chen Chun-Ming
Format: Article
Language:English
Published: BMC 2009-01-01
Series:Journal of Biomedical Science
Online Access:http://www.jbiomedsci.com/content/1/16/2

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