Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication

Genome duplication in Leishmania major relies on persistent subtelomeric DNA replication

DNA replication is needed to duplicate a cell’s genome in S phase and segregate it during cell division. Previous work in Leishmania detected DNA replication initiation at just a single region in each chromosome, an organisation predicted to be insufficient for complete genome duplication within S p...

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Bibliographic Details
Main Authors: Jeziel Dener Damasceno, Catarina A Marques, Dario Beraldi, Kathryn Crouch, Craig Lapsley, Ricardo Obonaga, Luiz RO Tosi, Richard McCulloch
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-09-01
Series:eLife
Subjects:
Leishmania
DNA replication
origin
subtelomere
Online Access:https://elifesciences.org/articles/58030

Internet

https://elifesciences.org/articles/58030

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