Nivolumab-induced synovitis is characterized by florid T cell infiltration and rapid resolution with synovial biopsy-guided therapy
Background Immune checkpoint inhibitors (ICIs) are associated with rheumatic and musculoskeletal immune-related adverse events (irAEs) in 5%–20% of patients. Currently, patients refractory to corticosteroids and conventional disease-modifying antirheumatic drugs (cDMARD) are treated with biological...
Main Authors: | William Murray-Brown, Tom D Wilsdon, Helen Weedon, Shawgi Sukumaran, Jennifer G Walker, Malcolm D Smith, Mihir D Wechalekar |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2020-06-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/8/1/e000281.full |
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