Effects of 5-aza-2´-deoxycytidine on primary human chondrocytes from osteoarthritic patients.

Chondrocytes, comparable to many cells from the connective tissue, dedifferentiate and end up in a similar fibroblastoid cell type, marked by the loss of the specific expression pattern. Here, chondrocytes isolated from osteoarthritic (OA) patients were investigated. The OA chondrocytes used in this...

Full description

Bibliographic Details
Main Authors: Shirin Kadler, Özlem Vural, Jennifer Rosowski, Luzia Reiners-Schramm, Roland Lauster, Mark Rosowski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0234641