Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor

Mechanisms and Treatment of Light-Induced Retinal Degeneration-Associated Inflammation: Insights from Biochemical Profiling of the Aqueous Humor

Ocular inflammation contributes to the pathogenesis of blind-causing retinal degenerative diseases, such as age-related macular degeneration (AMD) or photic maculopathy. Here, we report on inflammatory mechanisms that are associated with retinal degeneration induced by bright visible light, which we...

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Bibliographic Details
Main Authors: Dmitry V. Chistyakov, Viktoriia E. Baksheeva, Veronika V. Tiulina, Sergei V. Goriainov, Nadezhda V. Azbukina, Olga S. Gancharova, Eugene A. Arifulin, Sergey V. Komarov, Viktor V. Chistyakov, Natalia K. Tikhomirova, Andrey A. Zamyatnin, Pavel P. Philippov, Ivan I. Senin, Marina G. Sergeeva, Evgeni Yu. Zernii
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
ocular inflammation
light-induced retinal damage
age-related macular degeneration
oxidative stress
polyunsaturated fatty acids
oxylipins
mitochondria-targeted antioxidant
skq1
non-steroidal anti-inflammatory drugs
nepafenac
Online Access:https://www.mdpi.com/1422-0067/21/3/704

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https://www.mdpi.com/1422-0067/21/3/704

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