Myelin Disturbances Produced by Sub-Toxic Concentration of Heavy Metals: The Role of Oligodendrocyte Dysfunction

Myelin Disturbances Produced by Sub-Toxic Concentration of Heavy Metals: The Role of Oligodendrocyte Dysfunction

Evidence has been accumulated demonstrating that heavy metals may accumulate in various organs, leading to tissue damage and toxic effects in mammals. In particular, the Central Nervous System (CNS) seems to be particularly vulnerable to cumulative concentrations of heavy metals, though the pathophy...

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Bibliographic Details
Main Authors: Jessica Maiuolo, Roberta Macrì, Irene Bava, Micaela Gliozzi, Vincenzo Musolino, Saverio Nucera, Cristina Carresi, Miriam Scicchitano, Francesca Bosco, Federica Scarano, Ernesto Palma, Santo Gratteri, Vincenzo Mollace
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
heavy metals
oligodendrocytes
myelination
lipid formation
intracellular calcium regulation
Online Access:https://www.mdpi.com/1422-0067/20/18/4554

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