The use of tacrolimus for recurrent lupus enteritis: a case report

<p>Abstract</p> <p>Introduction</p> <p>Patients with lupus enteritis sometimes experience recurrence. In such cases, the addition of cyclophosphamide to the treatment regimen is recommended. However, an appropriate treatment has not been established in cases where cyclo...

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Bibliographic Details
Main Authors: Takasawa Naruhiko, Fujii Hiroshi, Tajima Yumi, Watanabe Ryu, Hirabayashi Yasuhiko, Shirai Tsuyoshi, Ishii Tomonori, Harigae Hideo
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Journal of Medical Case Reports
Online Access:http://www.jmedicalcasereports.com/content/4/1/150
Description
Summary:<p>Abstract</p> <p>Introduction</p> <p>Patients with lupus enteritis sometimes experience recurrence. In such cases, the addition of cyclophosphamide to the treatment regimen is recommended. However, an appropriate treatment has not been established in cases where cyclophosphamide failed to prevent the disease.</p> <p>Case presentation</p> <p>An 18-year-old Japanese woman was admitted for a recurrence of lupus enteritis. One year before admission she was treated for lupus enteritis with high-dose corticosteroid together with intravenous cyclophosphamide pulse therapy. Upon admission, she was administered again with high-dose corticosteroid and her abdominal pain rapidly subsided. Tacrolimus was later used as an immunosuppressive agent and a complete remission has been maintained.</p> <p>Conclusion</p> <p>Tacrolimus can be a useful agent for recurrent lupus enteritis that is resistant to conventional therapy.</p>
ISSN:1752-1947