The Nef Protein of the Macrophage Tropic HIV-1 Strain AD8 Counteracts Human BST-2/Tetherin

The Nef Protein of the Macrophage Tropic HIV-1 Strain AD8 Counteracts Human BST-2/Tetherin

Bone Marrow Stromal Cell Antigen 2 (BST-2)/tetherin inhibits the release of numerous enveloped viruses by physically tethering nascent particles to infected cells during the process of viral budding from the cell surface. Tetherin also restricts human immunodeficiency virus (HIV), and pandemic main...

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Bibliographic Details
Main Authors: Sebastian Giese, Scott P. Lawrence, Michela Mazzon, Bernadien M. Nijmeijer, Mark Marsh
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Viruses
Subjects:
BST-2
HIV-1
Nef
tetherin
macrophages
PBMC
Online Access:https://www.mdpi.com/1999-4915/12/4/459

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