Arginine Methylation of hnRNPK Inhibits the DDX3-hnRNPK Interaction to Play an Anti-Apoptosis Role in Osteosarcoma Cells

Arginine Methylation of hnRNPK Inhibits the DDX3-hnRNPK Interaction to Play an Anti-Apoptosis Role in Osteosarcoma Cells

Heterogeneous nuclear ribonucleoprotein K (hnRNPK) is an RNA/DNA binding protein involved in diverse cell processes; it is also a p53 coregulator that initiates apoptosis under DNA damage conditions. However, the upregulation of hnRNPK is correlated with cancer transformation, progression, and migra...

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Bibliographic Details
Main Authors: Chiao-Che Chen, Jen-Hao Yang, Shu-Ling Fu, Wey-Jinq Lin, Chao-Hsiung Lin
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
hnRNPK
DDX3
DNA damage
protein–protein interaction
Online Access:https://www.mdpi.com/1422-0067/22/18/9764

Internet

https://www.mdpi.com/1422-0067/22/18/9764

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