Protocol for <it>G</it>erman trial of <it>A</it>cyclovir and <it>c</it>orticosteroids in <it>H</it>erpes-simplex-virus-<it>e</it>ncephalitis (GACHE): a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial [ISRCTN45122933]

Protocol for <it>G</it>erman trial of <it>A</it>cyclovir and <it>c</it>orticosteroids in <it>H</it>erpes-simplex-virus-<it>e</it>ncephalitis (GACHE): a multicenter, multinational, randomized, double-blind, placebo-controlled German, Austrian and Dutch trial [ISRCTN45122933]

<p>Abstract</p> <p>Background</p> <p>The treatment of Herpes-simplex-virus-encephalitis (HSVE) remains a major unsolved problem in Neurology. Current gold standard for therapy is acyclovir, a drug that inhibits viral replication. Despite antiviral treatment, mortality r...

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Main Authors: Schielke Eva, Jensen Katrin, Jenetzky Ekkehart, Victor Norbert, Pritsch Maria, Menon Sanjay, Martinez-Torres Francisco, Schmutzhard Erich, de Gans Jan, Chung Chin-Hee, Luntz Steffen, Hacke Werner, Meyding-Lamadé Uta
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Neurology
Online Access:http://www.biomedcentral.com/1471-2377/8/40

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