C1q–HA Matrix Regulates the Local Synthesis of Hyaluronan in Malignant Pleural Mesothelioma by Modulating HAS3 Expression

C1q–HA Matrix Regulates the Local Synthesis of Hyaluronan in Malignant Pleural Mesothelioma by Modulating HAS3 Expression

Increased hyaluronic acid (HA) production is often associated with cancer progression. In malignant pleural mesothelioma (MPM), HA is found at elevated levels in pleural effusions and sera of patients, and it has been widely debated whether MPM cells are able to produce HA by themselves or through t...

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Bibliographic Details
Main Authors: Romana Vidergar, Andrea Balduit, Paola Zacchi, Chiara Agostinis, Alessandro Mangogna, Beatrice Belmonte, Micaela Grandolfo, Francesco Salton, Marco Biolo, Fabrizio Zanconati, Marco Confalonieri, Roberta Bulla
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Cancers
Subjects:
malignant pleural mesothelioma
cancer
hyaluronic acid
immune system
complement system
C1q
Online Access:https://www.mdpi.com/2072-6694/13/3/416

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