Empiric antibiotic treatment of lesser pelvis inflammatory diseases at the hospital stage
Acute salpingo-oophoritis treatment is based on the general principles of infectious pathology management and implies appropriate antibacterial therapy, which is often empiric. Meanwhile, though a number of new antibacterial medicines have appeared lately, it has not contributed to a reduction of th...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
IP Berlin A.V.
2013-02-01
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| Series: | Гинекология |
| Subjects: | |
| Online Access: | https://gynecology.orscience.ru/2079-5831/article/view/28172 |
| Summary: | Acute salpingo-oophoritis treatment is based on the general principles of infectious pathology management and implies appropriate antibacterial therapy, which is often empiric. Meanwhile, though a number of new antibacterial medicines have appeared lately, it has not contributed to a reduction of the frequency of lesser pelvis inflammatory diseases, which may result in female patients\' childbearing potential reduction. That is why analysing the efficacy and safety of the applied empiric antibiotic treatment regimens remains relevant. The results of the empiric antibiotic treatment of lesser pelvis inflammatory diseases at the hospital stage have been analysed. The data obtained indicate that the efficacy of the compared regimens which include ceftriaxone/cefotaxime in combination with doxycycline is the same. Moreover, it has been found that if the regimen is supplemented with a step application of ornidazole, clinical implications of the inflammatory process are characterised by a more apparent dynamics of regression, than if metronidazole is applied. The group of patients who received ornidazole was observed to show a higher tolerability of the antibacterial therapy than the metronidazole group. |
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| ISSN: | 2079-5696 2079-5831 |