Targeted Myoglobin Delivery as a Strategy for Enhancing the Sensitivity of Hypoxic Cancer Cells to Radiation

Summary: The effectiveness of cancer radiotherapy is frequently hindered by the hypoxia of the tumor microenvironment. Direct delivery of oxygen to hypoxic tumor tissues is an attractive strategy to overcome this hypoxia-associated radioresistance. Herein, we report the generation of submicron-sized...

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Bibliographic Details
Main Authors: Zaofeng Yang, Bradley S. Heater, Clayton T. Cuddington, Andre F. Palmer, Marianne M.M. Lee, Michael K. Chan
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220303436