pathVar: a new method for pathway-based interpretation of gene expression variability
Identifying the pathways that control a cellular phenotype is the first step to building a mechanistic model. Recent examples in developmental biology, cancer genomics, and neurological disease have demonstrated how changes in the variability of gene expression can highlight important genes that are...
Main Authors: | Laurence de Torrente, Samuel Zimmerman, Deanne Taylor, Yu Hasegawa, Christine A. Wells, Jessica C. Mar |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-05-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3334.pdf |
Similar Items
-
Addressing variability in iPSC-derived models of human disease: guidelines to promote reproducibility
by: Viola Volpato, et al.
Published: (2020-01-01) -
THE IMPACT OF INTER- AND INTRA-TUMORAL HETEROGENEITY ON THETREATMENT OF CANCER
by: Gopal, Priyanka
Published: (2019) -
Stochastic transcription in the p53‐mediated response to DNA damage is modulated by burst frequency
by: Dhana Friedrich, et al.
Published: (2019-12-01) -
Regionally Distinct Astrocytes Display Unique Transcription Factor Profiles in the Adult Brain
by: Brittney Lozzi, et al.
Published: (2020-02-01) -
Single-Cell Transcriptomics Bioinformatics and Computational Challenges
by: Lana Garmire, et al.
Published: (2016-09-01)