S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells

S100A9 Derived From Myeloma Associated Myeloid Cells Promotes TNFSF13B/TNFRSF13B-Dependent Proliferation and Survival of Myeloma Cells

Multiple myeloma (MM) is a lethal hematological malignancy characterized by abundant myeloid cells in the microenvironment that fuel tumor progression. But the mechanism by which myeloid cells support myeloma cells has not been fully explored. We aimed to examine their effect on bone marrow cells of...

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Bibliographic Details
Main Authors: Lingzhang Meng, Qiang Tang, Jingjie Zhao, Zechen Wang, Liuzhi Wei, Qiuju Wei, Lianfei Yin, Shiguan Luo, Jian Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Oncology
Subjects:
S100A9
TNFSF13B
myeloma
scRNA seq
tumor associated myeloid cells
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.691705/full

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