Advantages of the use of heterogeneous catalyst for Huisgen cycloaddition reaction: synthesis and application of new metalorganic material capable of regeneration and reuse

• Main Authors: Mônica Freire Belian, Moara Targino da Silva, Aline de Andrade Alves, Ronaldo Nascimento de Oliveira, Wagner Eduardo da Silva
• Format: Article
• Language: English
• Published: Universidade Estadual Paulista 2018-05-01
• Series: Eclética Química
• Online Access: https://revista.iq.unesp.br/ojs/index.php/ecletica/article/view/173

This works evaluates the catalytic capacity of metalorganic materials synthesized, based on Cu+ and ambidentade ligand in Huisgen cycloaddition reaction. The synthesis of 1,2,3-triazole was made using CuCl and CuI salts, and the [Cu(4,4’-dipy)]Cl and [Cu(4,4’-dipy)]I compounds as catalysts, with or without base catalysis by triethylamine. The copper salts and compounds lead to formation of the desired triazole product; however, in the synthesis mediated by [Cu(4,4’-dipy)]I does not generate the product, even after 48 h of reaction. The reaction with [Cu(4,4’-dipy)]Cl mediated or not by triethylamine showed high yields of 88 % and 70 %, respectively. The [Cu(4,4’-dipy)]Cl compounds was reused five times, and regenerated by ascorbic acid, maintaining thus, the same reaction yield.