Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5

Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5

Interleukin-10 is part of the immune response to urinary tract infection (UTI) due to E. coli, and it is important in the early control of infection in the bladder. Defining the mechanism of engagement of the immune system by the bacteria that enables the protective IL-10 response is critical to exp...

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Bibliographic Details
Main Authors: Dhruba Acharya, Matthew J. Sullivan, Benjamin L. Duell, Kelvin G. K. Goh, Lahiru Katupitiya, Dean Gosling, Michelle N. Chamoun, Asha Kakkanat, Debasish Chattopadhyay, Michael Crowley, David K. Crossman, Mark A. Schembri, Glen C. Ulett
Format: Article
Language:English
Published: American Society for Microbiology 2019-11-01
Series:mSphere
Subjects:
flagella
urinary tract infection
uropathogenic escherichia coli
Online Access:https://doi.org/10.1128/mSphere.00545-19

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