Intraluminal Administration of Resiniferatoxin Protects against Clostridium difficile Toxin A-Induced Colitis
Clostridium difficile toxin A is a colonic inflammatory agent that acts partially by activation of TRPV1 (transient receptor potential vanilloid type 1). Resiniferatoxin (RTX) is an excitotoxin that activates TRPV1 at low concentrations and defunctionalizes TRPV1 at high concentrations. RTX at vario...
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| Format: | Article |
| Language: | English |
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Hindawi Limited
2017-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2017/8438172 |