Development of an RNA Virus-Based Episomal Vector Capable of Switching Transgene Expression

Viral vectors are efficient gene delivery systems, although most of these vectors still present limitations to their practical use, such as achieving only transient transgene expression and a risk of insertional mutations. We have recently developed an RNA virus-based episomal vector (REVec), based...

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Bibliographic Details
Main Authors: Yusuke Yamamoto, Keizo Tomonaga, Tomoyuki Honda
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02485/full