Small Molecules Enhance Scaffold-Based Bone Grafts via Purinergic Receptor Signaling in Stem Cells

Small Molecules Enhance Scaffold-Based Bone Grafts via Purinergic Receptor Signaling in Stem Cells

The need for bone grafts is high, due to age-related diseases, such as tumor resections, but also accidents, risky sports, and military conflicts. The gold standard for bone grafting is the use of autografts from the iliac crest, but the limited amount of accessible material demands new sources of b...

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Bibliographic Details
Main Authors: Patrick Frank Ottensmeyer, Markus Witzler, Margit Schulze, Edda Tobiasch
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
purinergic receptors
mesenchymal stem cells
osteoclast
osteoblast
angiogenesis
bone
patent
scaffold
drug release
Online Access:https://www.mdpi.com/1422-0067/19/11/3601

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