Anticancer Drug-Induced Epithelial-Mesenchymal Transition via p53/miR-34a axis in A549/ABCA3 Cells
PURPOSE. Several anticancer drugs including bleomycin (BLM) and methotrexate (MTX) cause serious lung diseases such as pulmonary fibrosis. Although evidences showing the association of epithelial-mesenchymal transition (EMT) with pulmonary fibrosis are increasing, the mechanism underlying anticance...
Main Authors: | Ayano Yamamoto, Masashi Kawami, Takashi Konaka, Shinnosuke Takenaka, Ryoko Yumoto, Mikihisa Takano |
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Format: | Article |
Language: | English |
Published: |
Canadian Society for Pharmaceutical Sciences
2019-10-01
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Series: | Journal of Pharmacy & Pharmaceutical Sciences |
Online Access: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/30660 |
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