The Effect Of -401CT And -401CT Polymorphisms Of GGH Gene On Methotrexate Serum Level And Toxicity In Iranian Children With Acute Lymphoblastic Leukemia (ALL) Under Treatment In Ali Asghar Hospital In Tehran

The Effect Of -401CT And -401CT Polymorphisms Of GGH Gene On Methotrexate Serum Level And Toxicity In Iranian Children With Acute Lymphoblastic Leukemia (ALL) Under Treatment In Ali Asghar Hospital In Tehran

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Background and Aim: Acute lymphoblastic leukemia patients show differences in serum levels and toxicity associated with methotrexate after its treatment. Pharmacogenetics is an important determining factor for these differences. In this study, the effect of +452 C / T and -401C / T polymorphisms of...

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Bibliographic Details
Main Authors: Abolfazl Kalantari, Farhad Zaker, Shahla Ansari Damavandi, Heydar Sharafi, Seyed Amir Yazdanparast
Format: Article
Language:fas
Published: Tehran University of Medical Sciences 2015-01-01
Series:پیاورد سلامت
Subjects:
methotrexate
toxicity
children all
polymorphisms
Online Access:http://payavard.tums.ac.ir/article-1-5601-en.html
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