Potent anti-tumor effects of a dual specific oncolytic adenovirus expressing apoptin in vitro and in vivo

Potent anti-tumor effects of a dual specific oncolytic adenovirus expressing apoptin in vitro and in vivo

<p>Abstract</p> <p>Background</p> <p>Oncolytic virotherapy is an attractive drug platform of cancer gene therapy, but efficacy and specificity are important prerequisites for success of such strategies. Previous studies determined that Apoptin is a p53 independent, bcl-...

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Main Authors: Encheng Yang, Pegn Gao, Lili Sun, Kuoshi Jin, Mingyao Tian, Huijun Lu, Chang Li, Zhongmei Wen, Yan Liu, Xiao Li, Xiaohong Xu, Shifu Kan, Zhuoyue Wang, Yuhang Wang, Ningyi Jin
Format: Article
Language:English
Published: BMC 2010-01-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/10

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