Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

Thioredoxin peroxidase secreted by Echinococcus granulosus (sensu stricto) promotes the alternative activation of macrophages via PI3K/AKT/mTOR pathway

Abstract Background Larvae of Echinococcus granulosus (sensu lato) dwell in host organs for a long time but elicit only a mild inflammatory response, which indicates that the resolution of host inflammation is necessary for parasite survival. The recruitment of alternatively activated macrophages (A...

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Bibliographic Details
Main Authors: Hui Wang, Chuan-Shan Zhang, Bin-Bin Fang, Zhi-De Li, Liang Li, Xiao-Juan Bi, Wen-Ding Li, Ning Zhang, Ren-Yong Lin, Hao Wen
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Parasites & Vectors
Subjects:
Echinococcus granulosus (sensu lato)
Thioredoxin peroxidase
Excretory-secretory products
Peritoneal macrophages
Alternative activation
PI3K/AKT/mTOR pathway
Online Access:http://link.springer.com/article/10.1186/s13071-019-3786-z

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