Genetic alterations in syndromes with oral manifestations

• Main Authors: Krishnamurthy Anuthama, Harikrishnan Prasad, Pratibha Ramani, Priya Premkumar, Anuja Natesan, Herald J Sherlin
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2013-01-01
• Series: Dental Research Journal
• Subjects: Down′s syndrome; marfan′s syndrome; Rothmund Thomson syndrome
• Online Access: http://www.drjjournal.net/article.asp?issn=1735-3327;year=2013;volume=10;issue=6;spage=713;epage=722;aulast=Anuthama

Ever since Gregor Johan Mendel proposed the law of inheritance, genetics has transcended the field of health and has entered all walks of life in its application. Thus, the gene is the pivoting factor for all happenings revolving around it. Knowledge of gene mapping in various diseases would be a valuable tool in prenatally diagnosing the condition and averting the future disability and stigma for the posterity. This article includes an array of genetically determined conditions in patients seen at our college out-patient department with complete manifestation, partial manifestation and array of manifestations not fitting into a particular syndrome.