Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study

Safety, tolerability and impact on viral reservoirs of the addition to antiretroviral therapy of ABX464, an investigational antiviral drug, in individuals living with HIV-1: a Phase IIa randomised controlled study

Objectives: To assess the safety and tolerability as well as antiretroviral impact of ABX464, an oral investigational drug with a novel mechanism of HIV-1 inhibition (ClinicalTrials.gov NCT02735863). Methods: Randomised, double-blind, placebo-controlled, Phase IIa study in individuals living with HI...

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Bibliographic Details
Main Authors: Sofie Rutsaert, Jean-Marc Steens, Paul Gineste, Basiel Cole, Sam Kint, P. Noel Barrett, Jamal Tazi, Didier Scherrer, Hartmut J. Ehrlich, Linos Vandekerckhove
Format: Article
Language:English
Published: Elsevier 2019-01-01
Series:Journal of Virus Eradication
Subjects:
ABX464, safety, tolerability, HIV-1, Phase IIa study, HIV-1 reservoirs, viral rebound
Online Access:http://www.sciencedirect.com/science/article/pii/S2055664020302739

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http://www.sciencedirect.com/science/article/pii/S2055664020302739

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