Performance of single nucleotide polymorphisms versus haplotypes for genome-wide association analysis in barley.

Genome-wide association studies (GWAS) may benefit from utilizing haplotype information for making marker-phenotype associations. Several rationales for grouping single nucleotide polymorphisms (SNPs) into haplotype blocks exist, but any advantage may depend on such factors as genetic architecture o...

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Bibliographic Details
Main Authors: Aaron J Lorenz, Martha T Hamblin, Jean-Luc Jannink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2989918?pdf=render