Transient pentameric IgM fulfill biological function-Effect of expression host and transfection on IgM properties.
Recombinant production of IgM antibodies poses a special challenge due to the complex structure of the proteins and their not yet fully elucidated interactions with the immune effector proteins, especially the complement system. In this study, we present transient expression of IgM antibodies (IgM61...
Main Authors: | Julia Hennicke, Linda Schwaigerlehner, Clemens Grünwald-Gruber, Isabelle Bally, Wai Li Ling, Nicole Thielens, Jean-Baptiste Reiser, Renate Kunert |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2020-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0229992 |
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