Single Core Genome Sequencing for Detection of both <i>Borrelia burgdorferi</i> Sensu Lato and Relapsing Fever Borrelia Species

Single Core Genome Sequencing for Detection of both <i>Borrelia burgdorferi</i> Sensu Lato and Relapsing Fever Borrelia Species

Lyme disease, initially described as Lyme arthritis, was reported before nucleic-acid based detection technologies were available. The most widely used diagnostic tests for Lyme disease are based on the serologic detection of antibodies produced against antigens derived from a single strain of <i...

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Bibliographic Details
Main Authors: Sin Hang Lee, John Eoin Healy, John S Lambert
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Environmental Research and Public Health
Subjects:
Lyme disease
core genome
DNA sequencing
borreliosis
relapsing fever borreliae
metagenomic diagnosis
<i>Borrelia</i>
genus-specific PCR primers
second PCR
direct detection
Sanger sequencing
Online Access:https://www.mdpi.com/1660-4601/16/10/1779

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