Statin Therapy Alters Lipid Storage in Diabetic Skeletal Muscle.

Statin Therapy Alters Lipid Storage in Diabetic Skeletal Muscle.

While statins significantly reduce cholesterol levels and thereby reduce the risk of cardiovascular disease, the development of myopathy with statin use is a significant clinical side-effect. Recent guidelines recommend increasing inclusion criteria for statin treatment in diabetic individuals; howe...

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Bibliographic Details
Main Authors: Irena A Rebalka, Matthew J Raleigh, Laelie A Snook, Alexandra N Rebalka, Rebecca EK MacPherson, David C Wright, Jonathan D Schertzer, Thomas J Hawke
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-07-01
Series:Frontiers in Endocrinology
Subjects:
skeletal muscle
Myopathy
Fluvastatin
FABPpm
FAT/CD36
Ectopic lipids
Online Access:http://journal.frontiersin.org/Journal/10.3389/fendo.2016.00095/full

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