Infection and depletion of CD4+ group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway.

Infection and depletion of CD4+ group-1 innate lymphoid cells by HIV-1 via type-I interferon pathway.

Innate lymphoid cells (ILCs) are severely depleted during chronic HIV-1 infection by unclear mechanisms. We report here that human ILC1s comprising of CD4+ and CD4- subpopulations were present in various human lymphoid organs but with different transcription programs and functions. Importantly, CD4+...

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Bibliographic Details
Main Authors: Juanjuan Zhao, Liang Cheng, Hongbo Wang, Haisheng Yu, Bo Tu, Qiang Fu, Guangming Li, Qi Wang, Yanling Sun, Xin Zhang, Zhenwen Liu, Weiwei Chen, Liguo Zhang, Lishan Su, Zheng Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5773236?pdf=render

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