Transmembrane Facilitation of Lactate/H<sup>+</sup> Instead of Lactic Acid Is Not a Question of Semantics but of Cell Viability

Transmembrane Facilitation of Lactate/H<sup>+</sup> Instead of Lactic Acid Is Not a Question of Semantics but of Cell Viability

Transmembrane transport of monocarboxylates is conferred by structurally diverse membrane proteins. Here, we describe the pH dependence of lactic acid/lactate facilitation of an aquaporin (AQP9), a monocarboxylate transporter (MCT1, SLC16A1), and a formate–nitrite transporter (plasmodium falciparum...

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Bibliographic Details
Main Authors: Annika Bader, Eric Beitz
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Membranes
Subjects:
lactic acid
lactate
proton
transport
energy metabolism
aquaporin
Online Access:https://www.mdpi.com/2077-0375/10/9/236

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