Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type

Combining phenotypic and proteomic approaches to identify membrane targets in a ‘triple negative’ breast cancer cell type

<p>Abstract</p> <p>Background</p> <p>The continued discovery of therapeutic antibodies, which address unmet medical needs, requires the continued discovery of tractable antibody targets. Multiple protein-level target discovery approaches are available and these can be u...

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Bibliographic Details
Main Authors: Rust Steven, Guillard Sandrine, Sachsenmeier Kris, Hay Carl, Davidson Max, Karlsson Anders, Karlsson Roger, Brand Erin, Lowne David, Elvin John, Flynn Matt, Kurosawa Gene, Hollingsworth Robert, Jermutus Lutz, Minter Ralph
Format: Article
Language:English
Published: BMC 2013-02-01
Series:Molecular Cancer
Subjects:
Phage display
Hybridoma
Antibody
Phenotypic screening
Membranome
CD73
Online Access:http://www.molecular-cancer.com/content/12/1/11

Internet

http://www.molecular-cancer.com/content/12/1/11

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