The effect of ongoing exposure dynamics in dose response relationships.

Characterizing infectivity as a function of pathogen dose is integral to microbial risk assessment. Dose-response experiments usually administer doses to subjects at one time. Phenomenological models of the resulting data, such as the exponential and the Beta-Poisson models, ignore dose timing and a...

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Bibliographic Details
Main Authors: Josep M Pujol, Joseph E Eisenberg, Charles N Haas, James S Koopman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2685010?pdf=render