The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls

The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls

Background   Regarding abnormalities in thalassemia major (TM) patients and the effects of leptin and ferritin on heart, aimed to investigate the possible relationship between leptin, ferritin and cardiac involvement in TM patients compared to controls.   Materials and Methods   In total 141 indiv...

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Main Authors: Noor Mohammad Noori, Amer Yazdanparast, Alireza Teimouri
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2018-05-01
Series:International Journal of Pediatrics
Subjects:
Cardiac findings
Children
Ferritin
Leptin
Beta- Thalassemia
Online Access:http://ijp.mums.ac.ir/article_10548_00bfcf3439396b33ddc3fdec36e14bb0.pdf
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spelling doaj-3ebf9506bf284efd86c1f0ef2a44b7a02020-11-25T02:00:19ZengMashhad University of Medical SciencesInternational Journal of Pediatrics2345-50472345-50552018-05-01657623763810.22038/ijp.2018.29137.254410548The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to ControlsNoor Mohammad Noori0Amer Yazdanparast1Alireza Teimouri2Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran.Assistant Perofessor of Pediatric Cardiology, Department of Pediatrics, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.Children and Adolescent Health Research Center, Resistant Tuberculosis Institute, Zahedan University of Medical Sciences, Zahedan, Iran.Background   Regarding abnormalities in thalassemia major (TM) patients and the effects of leptin and ferritin on heart, aimed to investigate the possible relationship between leptin, ferritin and cardiac involvement in TM patients compared to controls.   Materials and Methods   In total 141 individuals entered to the present case-control study that consisted of 66 TM patients matched in age and sex with 75 healthy controls. The case group selected from those patients attending to the clinic of Ali Asghar Hospital, Zahedan-Iran. From participants, 5ml blood takes by a nurse and was isolated from serum samples in order to analyze ferritin and leptin levels. Major proceedings in patients were checking medical history, physical examination, chest X-ray and Electrocardiogram (ECG) that performed before echocardiography by unique cardiologist. The participants subjected to conventional examination for both right and left heart functions.   Results   Leptin level (p=0.026), height, weight and body mass index (BMI) were lower in patients (phttp://ijp.mums.ac.ir/article_10548_00bfcf3439396b33ddc3fdec36e14bb0.pdfCardiac findingsChildrenFerritinLeptinBeta- Thalassemia
collection DOAJ
language English
format Article
sources DOAJ
author Noor Mohammad Noori
Amer Yazdanparast
Alireza Teimouri
spellingShingle Noor Mohammad Noori
Amer Yazdanparast
Alireza Teimouri
The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls
International Journal of Pediatrics
Cardiac findings
Children
Ferritin
Leptin
Beta- Thalassemia
author_facet Noor Mohammad Noori
Amer Yazdanparast
Alireza Teimouri
author_sort Noor Mohammad Noori
title The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls
title_short The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls
title_full The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls
title_fullStr The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls
title_full_unstemmed The Correlation of Ferritin and Leptin Serum Levels with Cardiac Involvement in Thalassemia Patients Compared to Controls
title_sort correlation of ferritin and leptin serum levels with cardiac involvement in thalassemia patients compared to controls
publisher Mashhad University of Medical Sciences
series International Journal of Pediatrics
issn 2345-5047
2345-5055
publishDate 2018-05-01
description Background   Regarding abnormalities in thalassemia major (TM) patients and the effects of leptin and ferritin on heart, aimed to investigate the possible relationship between leptin, ferritin and cardiac involvement in TM patients compared to controls.   Materials and Methods   In total 141 individuals entered to the present case-control study that consisted of 66 TM patients matched in age and sex with 75 healthy controls. The case group selected from those patients attending to the clinic of Ali Asghar Hospital, Zahedan-Iran. From participants, 5ml blood takes by a nurse and was isolated from serum samples in order to analyze ferritin and leptin levels. Major proceedings in patients were checking medical history, physical examination, chest X-ray and Electrocardiogram (ECG) that performed before echocardiography by unique cardiologist. The participants subjected to conventional examination for both right and left heart functions.   Results   Leptin level (p=0.026), height, weight and body mass index (BMI) were lower in patients (p
topic Cardiac findings
Children
Ferritin
Leptin
Beta- Thalassemia
url http://ijp.mums.ac.ir/article_10548_00bfcf3439396b33ddc3fdec36e14bb0.pdf
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