AKTIVITAS ANTIBAKTERI LOTION MINYAK KAYU MANIS TERHADAP Staphylococcus epidermidis PENYEBAB BAU KAKI

• Main Authors: Fitri Apriliyani Tiran, Christofori M.R.R. Nastiti
• Format: Article
• Language: English
• Published: Universitas Sanata Dharma 2016-04-01
• Series: Jurnal Farmasi Sains dan Komunitas
• Online Access: http://e-journal.usd.ac.id/index.php/JFSK/article/view/103

Abstract: Trans-cinnamaldehyde is the major chemical compound of cinnamon oil which is potential as an antibacterial agent. Due to this activity, Cinnamon oil can be formulated into a lotion for practical use. This study aimed to determine the antibacterial activity of cinnamon oil and cinnamon oil lotion against Staphylococcus epidermidis, which causes unacceptable foot odor. This study was a pure experimental study. Stages of this study were starting from the obsevation of antibacterial activity of Cinnamon oil against Staphylococcus epidermidis which was done by using diffusion method to determine the concentrations used in the formulation. Cinnamon oil was then formulated into lotions with variation of concentrations of 12; 18; and 24% (w/w) respectively. Furthermore, the quality of lotion based on its physical properties such as viscosity and spread-ability, and the antibacterial activity of lotion were determined. The inhibition zones then were statistically analyzed by using the Kruskal-Wallis test with assistance of R 2.14.1software. The result showed that cinnamon oil lotion had good physical properties at a concentration of 12% (w/w). Cinnamon oil itself and the formulations had significant activity against Staphylococcus epidermidis. Moreover, cinnamon oil and its formulation showed similar antibacterial activity against Staphylococcus epidermidis. Keywords : antibacterial activity, cinnamon oil, lotion, Staphylococcus epidermidis