Single-cell RNA sequencing of cultured human endometrial CD140b+CD146+ perivascular cells highlights the importance of in vivo microenvironment

Single-cell RNA sequencing of cultured human endometrial CD140b+CD146+ perivascular cells highlights the importance of in vivo microenvironment

Abstract Background Endometrial mesenchymal-like stromal/stem cells (eMSCs) have been proposed as adult stem cells contributing to endometrial regeneration. One set of perivascular markers (CD140b&CD146) has been widely used to enrich eMSCs. Although eMSCs are easily accessible for regenerative...

Full description

Bibliographic Details
Main Authors: Dandan Cao, Rachel W. S. Chan, Ernest H. Y. Ng, Kristina Gemzell-Danielsson, William S. B. Yeung
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Stem Cell Research & Therapy
Subjects:
Endometrial perivascular cells
Single-cell RNA sequencing
Heterogeneity
Microenvironment
Online Access:https://doi.org/10.1186/s13287-021-02354-1

Internet

https://doi.org/10.1186/s13287-021-02354-1

Similar Items