In vitro screening of 1-aryl-6-hydroxy-1,2,3,4-tetrahydroisoquinolines: Structure related activity against pathogenic bacteria

In vitro screening of 1-aryl-6-hydroxy-1,2,3,4-tetrahydroisoquinolines: Structure related activity against pathogenic bacteria

Objective: To evaluate the antibacterial activity of ten synthetic tetrahydroisoquinolines against eight bacterial strains. Methods: The ten tetrahydroisoquinolines synthesized via base-catalyzed Pictet–Spengler cyclization were screened against a total of eight bacterial strains comprising control...

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Bibliographic Details
Main Authors: Moses Njutain Ngemenya, Joelle Ngo Hanna, Julios Armand Komtchou, Simon Mbua Ngale Efange
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-06-01
Series:Asian Pacific Journal of Tropical Biomedicine
Subjects:
Antibiotics
Drug discovery
Antibacterial agents
Tetrahydroisoquinolines
Cytotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S2221169115000726

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http://www.sciencedirect.com/science/article/pii/S2221169115000726

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