Plant-produced recombinant Osteopontin-Fc fusion protein enhanced osteogenesis
Osteopontin (OPN) plays an important role in the bone regeneration process. Previous investigation showed that recombinant human OPN was able to express in Nicotiana benthamiana leaves and induced the osteogenic related genes. Nevertheless, the purification of OPN from plant proteins with Ni affinit...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-03-01
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Series: | Biotechnology Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2215017X18303400 |