Plant-produced recombinant Osteopontin-Fc fusion protein enhanced osteogenesis

Osteopontin (OPN) plays an important role in the bone regeneration process. Previous investigation showed that recombinant human OPN was able to express in Nicotiana benthamiana leaves and induced the osteogenic related genes. Nevertheless, the purification of OPN from plant proteins with Ni affinit...

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Bibliographic Details
Main Authors: Kaewta Rattanapisit, Suchada Srifa, Pornjira Kaewpungsup, Prasit Pavasant, Waranyoo Phoolcharoen
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Biotechnology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X18303400