Association between EcoRI fragment-length polymorphism of the immunoglobulin lambda variable 8 (IGLV8) gene family with rheumatoid arthritis and systemic lupus erythematosus

Association between EcoRI fragment-length polymorphism of the immunoglobulin lambda variable 8 (IGLV8) gene family with rheumatoid arthritis and systemic lupus erythematosus

The human immunoglobulin lambda variable 8 (IGLV8) subgroup is a gene family containing three members, one of them included in a monomorphic 3.7-kb EcoRI genomic fragment located at the major lambda variable locus on chromosome 22q11.1 (gene IGLV8a, EMBL accession No. Z73650) at 100% frequency in th...

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Bibliographic Details
Main Authors: Queiroz R.G.P., Tamia-Ferreira M.C., Carvalho I.F., Petean F.C., Passos G.A.S.
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2001-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
rheumatoid arthritis
systemic lupus erythematosus
human V-lambda 8 genes
polymorphism of V-lambda genes
RFLP-disease association
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2001000400013

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