Neovascularization of coronary <it>tunica intima</it> (DIT) is the cause of coronary atherosclerosis. Lipoproteins invade coronary intima via neovascularization from adventitial <it>vasa vasorum</it>, but not from the arterial lumen: a hypothesis
<p>Abstract</p> <p>Background</p> <p>An accepted hypothesis states that coronary atherosclerosis (CA) is initiated by endothelial dysfunction due to inflammation and high levels of LDL-C, followed by deposition of lipids and macrophages from the luminal blood into the a...
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Format: | Article |
Language: | English |
Published: |
BMC
2012-04-01
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Series: | Theoretical Biology and Medical Modelling |
Online Access: | http://www.tbiomed.com/content/9/1/11 |