Neovascularization of coronary <it>tunica intima</it> (DIT) is the cause of coronary atherosclerosis. Lipoproteins invade coronary intima via neovascularization from adventitial <it>vasa vasorum</it>, but not from the arterial lumen: a hypothesis

<p>Abstract</p> <p>Background</p> <p>An accepted hypothesis states that coronary atherosclerosis (CA) is initiated by endothelial dysfunction due to inflammation and high levels of LDL-C, followed by deposition of lipids and macrophages from the luminal blood into the a...

Full description

Bibliographic Details
Main Author: Subbotin Vladimir M
Format: Article
Language:English
Published: BMC 2012-04-01
Series:Theoretical Biology and Medical Modelling
Online Access:http://www.tbiomed.com/content/9/1/11